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A method to register THz and visible images of cutaneous burn wounds and to calibrate THz image data is presented. Images of partial and full thickness burn wounds in 9 rats were collected over 435 mins. = 7.25 hours following burn induction. A two-step process was developed to reference the unknown structure of THz imaging contrast to the known structure and the features present in visible images of the injury. This process enabled the demarcation of a wound center for each THz image,doi:10.1364/boe.10.000322 pmid:30775103 pmcid:PMC6363189 fatcat:hy7nlldqhfhche5bclrtwtcpqa