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Laser-induced photoacoustic tomography enhanced with an optical contrast agent
2004
Photons Plus Ultrasound: Imaging and Sensing
Optical contrast agents, such as indocyanine dyes, nano-particles and their functional derivatives, have been widely applied to enhance the sensitivity and specificity of optical imaging. However, due to the overwhelming scattering of light in biological tissues, the spatial resolution of traditional optical imaging degrades drastically as the imaging depth increases. For the first time to our knowledge, non-invasive in vivo photoacoustic imaging of an optical contrast agent, distributed in the
doi:10.1117/12.532434
fatcat:iz7ahy2rkff5dieiehnyhje4g4