When a early gastric cancer is associated with ulcer or ulcer scar, endoscopic mucosal resection is difficult because the lesion is not held by a injection of normal saline into a submucosal layer under a lesion. Endoscopic treatment for this type of early gastric cancer is limited only by a tissue coagulation method. We performed laser irradiation on 20 cases of this type of early gastric cancer which surgical treatment was considered to be a high risk. A Nd-YAG laser was applied by the

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... tact method with an output of 50-70 Watt. Final cancer free rate for over all cases was 85.0%(17/20) and 88.9% for differentiated type of adenocarcinoma, 81.8% for undifferentiated type. Comparing with early gastric cancers without ulcerative changes, those required more cycles of irradiation.