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Variation in the In Vitro Migration of Sensitized Guinea Pig Peritoneal Exudate Cells in the Presence of Coccidioidin
1974
Infection and Immunity
Guinea pigs were immunized by intramuscular injection of arthrospores from the Mll strain of Coccidioides immitis, and the peritoneal exudate cells were harvested 4 to 6 weeks later. After incubation with various concentrations of coccidioidin in tissue culture, the area of all migration was measured. Results of this study indicate that at a critical level, a variance of 0.1 sg of antigen per ml, determined the difference between approximately 88% migration and 5% migration as compared with
doi:10.1128/iai.9.2.416-418.1974
fatcat:3bvzh77b35djxddkevostnmpwu