The secure boot-up and setup of Internet of Things (IoT) devices connected over the Cloud represent a challenging open issue. This paper deals with the automatic configuration of IoT devices in a secure way through the Cloud, in order to provide new addedvalue services. After a discussion on the limits of current IoT and Cloud solutions in terms of secure self-configuration, we present a Cloud-based architecture that allows IoT devices to interact with several federated Cloud providers. In

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... cular, we present two possible scenarios, that is, single Cloud and a federated Cloud environments, interacting with IoT devices and we address specific issues of both. Moreover, we present several design highlights on how to operate considering real open hardware and software products already available in the market.