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An Alternative Splicing Program for Mouse Craniofacial Development
2020
Frontiers in Physiology
Alternative splicing acts as a fundamental mechanism to increase the number of functional transcripts that can be derived from the genome - and its appropriate regulation is required to direct normal development, differentiation, and physiology, in many species. Recent studies have highlighted that mutation of splicing factors, resulting in the disruption of alternative splicing, can have profound consequences for mammalian craniofacial development. However, there has been no systematic
doi:10.3389/fphys.2020.01099
pmid:33013468
pmcid:PMC7498679
fatcat:st3vhfx4a5b45n2vc47vbjwc2i