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The cybrid model of sporadic Parkinson's disease
2009
Experimental Neurology
Parkinson's disease (PD) is the eponym attached to the most prevalent neurodegenerative movement disorder of adults, derived from observations of an early nineteenth century physician and paleontologist, James Parkinson, and is now recognized to encompass much more than a movement disorder clinically or dopamine neuron death pathologically. Most PD (~90%) is sporadic (sPD), is associated with mitochondrial deficiencies and has been studied in cell and animal models arising from use of
doi:10.1016/j.expneurol.2009.03.016
pmid:19328199
pmcid:PMC2735256
fatcat:jqe6hdop55f67cj67cpolvleqy