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Human vascular smooth muscle cell DNA synthesis stimulated by native low density lipoproteins involves redox-sensitive pathways. Inhibition by N-acetylcysteine and green tea constituents
2001
High plasma concentrations of LDL are an important cardiovascular risk factor. The mechanisms involved in DNA synthesis induced by native LDL in human vascular smooth muscle cells are unclear. We investigated the potential role of oxidative stress in human vascular smooth muscle cells (VSMC) DNA synthesis using the antioxidant N-acetylcysteine (NAC) and different green tea catechins, i. e. epigallocatechin (EGC), epigallocatechin gallate (EGCg) and green tea polyphenon, a mixture of green tea
doi:10.5167/uzh-154278
fatcat:s7xky6vewfddfnrq6oc4iin7bq