Fabrication of three-dimensional proteinaceous micro- and nano-structures by femtosecond laser cross-linking

Daniela Serien, Koji Sugioka
2018 Opto-Electronic Advances  
Proteins are a class of biomaterials having a vast array of functions, including the catalysis of metabolic reactions, DNA replication, stimuli response and transportation of molecules. Recent progress in laser-based fabrication technologies has enabled the formation of three-dimensional (3D) proteinaceous micro-and nano-structures by femtosecond laser cross-linking, which has expanded the possible applications of proteins. This article reviews the current knowledge and recent advancements in
more » ... e femtosecond laser cross-linking of proteins. An overview of previous studies related to fabrication using a variety of proteins and detailed discussions of the associated mechanisms are provided. In addition, advances and applications utilizing specific protein functions are introduced. This review thus provides a valuable summary of the 3D micro-and nano-fabrication of proteins for biological and medical applications.
doi:10.29026/oea.2018.180008 fatcat:chmd3zlufzf2zmvmd437wyeoqa