In the article the influence of using the microencapsulated probiotic preparation Enzymesporine with an enzyme in comparison with analogues that do not have an enzyme (microencapsulated and non-encapsulated) in pigs of Genesus selection is considered. The activity on intestinal digestion, growth and weight gain, and on hematological and biochemical parameters is studied. The period of life of pigs during the experiment was 48-98-148 days. In the course of the performed experiment on pigs of

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... sus selection, after the usage of reliable results. The increase in the life weight and daily weight gain in the period from the 48th to the 148th day of life has been confirmed. That indicates the advantages of the microencapsulated probiotic preparation Enzymesporine with an enzyme over microencapsulated and non-encapsulated analogues without an enzyme. The general analysis of blood showed that the animals that received microencapsulated Enzymesporine with an enzyme. Along with that the content of erythrocytes and hemoglobin reached the upper physiological limit, which is significantly higher than that in the control groups. During the determination of biochemical parameters of blood a significant increase of the amount of total protein and albumins in experimental animals was detected up to 148 days of animals' life. A significantly high level of immunoglobulins was observed throughout the experiment in the tested animals. When comparing with the control group, that indicates a high resistance to diseases and a high immune status of pigs.