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RNAcentral: a hub of information for non-coding RNA sequences

Blake A Sweeney, Anton I Petrov, Boris Burkov, Robert D Finn, Alex Bateman, Maciej Szymanski, Wojciech M Karlowski, Jan Gorodkin, Stefan E Seemann, Jamie J Cannone, Robin R Gutell, Petra Fey (+49 others)
2018 Nucleic Acids Research  

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RNAcentral is a comprehensive database of noncoding RNA (ncRNA) sequences, collating informa-tion on ncRNA sequences of all types from a broad range of organisms. We have recently added a new genome mapping pipeline that identifies genomic lo-cations for ncRNA sequences in 296 species. We have also added several new types of functional annotations, such as tRNA secondary structures, Gene Ontology annotations, and miRNA-target interactions. A new quality control mechanism based on Rfam family
more » ... ignments identifies potential contamination, incomplete sequences, and more. The RNAcentral database has become a vital component of many workflows in the RNA community, serving as both the primary source of sequence data for academic and commercial groups, as well as a source of stable accessions for the annotation of genomic and functional features. These examples are facilitated by an improved RNAcentral web interface, which features an updated genome browser, a new sequence feature viewer, and improved text search functionality. RNAcentral is freely available at https://rnacentral.org.
doi:10.1093/nar/gky1034 pmid:30395267 fatcat:cpskjl3j6bd5hhpehf6ighpjfa
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Blake A Sweeney, Anton I Petrov, Boris Burkov, Robert D Finn, Alex Bateman, Maciej Szymanski, Wojciech M Karlowski, Jan Gorodkin, Stefan E Seemann, Jamie J Cannone, Robin R Gutell, Petra Fey, Siddhartha Basu, Simon Kay, Guy Cochrane, Kostantinos Billis, David Emmert, Steven J Marygold, Rachael P Huntley, Ruth C Lovering, Adam Frankish, Patricia P Chan, Todd M Lowe, Elspeth Bruford, Ruth Seal, Jo Vandesompele, Pieter-Jan Volders, Maria Paraskevopoulou, Lina Ma, Zhang Zhang, Sam Griffiths-Jones, Janusz M Bujnicki, Pietro Boccaletto, Judith A Blake, Carol J Bult, Runsheng Chen, Yi Zhao, Valerie Wood, Kim Rutherford, Elena Rivas, James Cole, Stanley J F Laulederkind, Mary Shimoyama, Marc E Gillespie, Marija Orlic-Milacic, Ioanna Kalvari, Eric Nawrocki, Stacia R Engel, J Michael Cherry, SILVA Team, Tanya Z Berardini, Artemis Hatzigeorgiou, Dimitra Karagkouni, Kevin Howe, Paul Davis, Marcel Dinger, Shunmin He, Maki Yoshihama, Naoya Kenmochi, Peter F Stadler, Kelly P Williams. "RNAcentral: a hub of information for non-coding RNA sequences." Nucleic Acids Research 47.D1 (2018) D221-D229