RNAcentral: a hub of information for non-coding RNA sequences

Blake A Sweeney, Anton I Petrov, Boris Burkov, Robert D Finn, Alex Bateman, Maciej Szymanski, Wojciech M Karlowski, Jan Gorodkin, Stefan E Seemann, Jamie J Cannone, Robin R Gutell, Petra Fey (+49 others)
2018 Nucleic Acids Research  
RNAcentral is a comprehensive database of noncoding RNA (ncRNA) sequences, collating informa-tion on ncRNA sequences of all types from a broad range of organisms. We have recently added a new genome mapping pipeline that identifies genomic lo-cations for ncRNA sequences in 296 species. We have also added several new types of functional annotations, such as tRNA secondary structures, Gene Ontology annotations, and miRNA-target interactions. A new quality control mechanism based on Rfam family
more » ... ignments identifies potential contamination, incomplete sequences, and more. The RNAcentral database has become a vital component of many workflows in the RNA community, serving as both the primary source of sequence data for academic and commercial groups, as well as a source of stable accessions for the annotation of genomic and functional features. These examples are facilitated by an improved RNAcentral web interface, which features an updated genome browser, a new sequence feature viewer, and improved text search functionality. RNAcentral is freely available at https://rnacentral.org.
doi:10.1093/nar/gky1034 pmid:30395267 fatcat:cpskjl3j6bd5hhpehf6ighpjfa