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Vascular hemodynamics is central to the regulation of neuro-metabolism and plays important roles in peripheral nerves diseases and their prevention. However, at present there are only a few techniques capable of directly measuring peripheral nerve vascular hemodynamics. Here, we investigate the use of dark-field functional photoacoustic microscopy (fPAM) for intrinsic visualizing of the relative hemodynamics of the rat sciatic nerve in response to localized temperature modulation (i.e., coolingdoi:10.1186/1475-925x-12-120 pmid:24245952 pmcid:PMC4225521 fatcat:ctmrnl5tm5hlvbvy43riaw3rae