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Introduction Systemic lupus erythematosus (SLE) is a systemic autoimmune disorder that commonly affects the heart. The impact of SLE on the heart is a 7-9 times greater incidence of cardiovascular disease(CVD) in SLE patients compared to healthy controls. Moreover, female patients with SLE between 35 and 44 years old have an incidence of myocardial infarction over 50 times greater than that observed in the Framingham cohort. The exact cause of this excess CVD burden in SLE is poorly understood,doi:10.1136/heartjnl-2013-304019.100 fatcat:fqewphh67fhevdvbtcaxkof6hi