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NK cell phenotypic and functional shifts coincide with specific clinical phases in the natural history of chronic HBV infection
2017
Antiviral Research
Word Count: 206 words (excluding section titles) Abstract: Background: Chronic HBV infection can be divided into 4 distinct clinical phases: immune tolerant, immune active, inactive carrier, and HBeAg-negative hepatitis. Using a systems biology approach, we recently identified innate immune response components, specifically NK cells as a distinctive factor of specific HBV clinical phases. To expand on this study and identify the underlying immunological mechanisms, we performed a comprehensive
doi:10.1016/j.antiviral.2017.01.007
pmid:28093337
fatcat:y4krd4yc7ndn7iyyu63npabo6i