Antibiotic prescriptions for COVID-19 patients increased during the BA.5 period

Sayaka Ebina, Masafumi Seki, Haruka Karaushi, Atsuko Shimizu, Kotaro Mitsutake
2023 Trends Journal of Sciences Research  
The initial omicron (B.1.1.529) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) subvariants, BA.1 and BA.2 (BA.1/2), were progressively displaced by BA.5 in Japan, which showed not only higher transmittivity and less pathogenicity, but also differences in antibiotic use according to the difference in the clinical course of BA.5 compared with BA.1/2 infections. BA.5 patients received more antibiotics, especially ampicillin/sulbactam, although ceftriaxone and meropenem were used
more » ... ficantly in the BA.1/2 period. These data suggest an increased incidence of aspiration pneumonia in elderly patients in the BA.5 period, and we should consider changing the management tactics for COVID-19.
doi:10.31586/wjmm.2023.579 fatcat:wuegronmajduvmgwp2ynekpwsu