Neoclerodanes from Teucrium orientale

Maurizio Bruno, Sergio Rosselli, Antonella Maggio, Franco Piozzi, Leonardo Scaglioni, Nelly A. Arnold, Monique S. J. Simmonds
2004 Chemical and pharmaceutical bulletin  
The chemistry of the genus Teucrium (Lamiaceae) has been investigated by our group for the last forty years. It contains more than 300 species, 1) many of them occurring in the Mediterranean region. 2) To date, the only diterpenoids isolated from the aerial parts of Teucrium are those with a neoclerodane skeleton. More than 220 diterpenes have been described, all differing in the functional groups on the neoclerodane or 19-nor-neoclerodane skeleton. 3-6) These secondary metabolites are of
more » ... st because of their ecological role as antifeedant against some species of insects, 7-9) and potential role in the medicinal properties of the plants. [10] [11] [12] [13] [14] [15] [16] [17] [18] As part of our investigations of this genus, we report here the results of the phytochemical analysis of Teucrium orientale L., a species occurring in the Lebanon-Syria-Israel-Jordan area. The sample of Teucrium orientale now investigated comes from Lebanon, where is named "oja'dah sharqiyah". It is botanically similar to Teucrium oliverianum (GING. ex BENTH.) R.Br., a species occurring in the area from Jordan to Saudi Arabia from which many compounds were isolated. [19] [20] [21] [22] [23] [24]
doi:10.1248/cpb.52.1497 pmid:15577256 fatcat:oonrro34mjh3tkoxrpbwqpecbi