Primary carcinoma of the liver

J. M. Beattie, R. Donaldson
1912 The Journal of Pathology and Bacteriology  
E;.om thc l ' d h u l ( q y J)cpurlwieiaf, U?iicercTsily of Shrfldd. (PLATES V1.-VIII.) TIIE following case, which came under our notice in the early pnrt of this year, illustrates a condition of considerable rarity and presents several features of interest. The vliiiiid record is v i~y imperfect, but the following facts were elicitell. The patient, a h 64, was admitted to hospital on account of increasing abilominal tlistension. The onset MYIS soiiiewl~nt insidious, and the duration of illness
more » ... duration of illness caxtcmded ovt"~ a consitlerable period. There were no gastric symptoms. A nodnlor iiiiws c-ould be felt in tlic region of thc liver whose margin conld be Post-mortem Examination. n1apped out. 0 1 1 post-morteiii examination the body was very markedly eniaciaterl and tleeply jaundiced. Except in the liver tliere was nothing of spccial importance iri any of the orgins. Tlic epicardiuni was somewhat thic:kened and thc veasels were distinctly tortoous rind tliialtened. The lower lobcs were congested, but there was no sign oi pneumonia. S o maligiiant disease c o d d be found. Abdouien.-On opening tlw abdomen tlioro escaped consitlernble quantity of blood-stained h i d . S'tonznch and Infesfinm--No malignant disease, ulcer, or other patl~ological raontlition was discovered. Spleen.-This organ wag not enlarged, but it was in it state of clironio venous congestion. h e fibrous tissue throughout was very prominent. Puncreas.-Ko trace of inalignanry could be detected, and it was otherwise 1ie:iltliy. ~<i&ze~ys.---'l'li usc presen tell the appearance of an interstitinl nephritis. The capsule was tliickenetl and adherent, the surface granular, and on section tlie deep cortex was found atrophied. Tho vessels were distinctly thickcnetl. Litey.-The liver was very much enlarged and presented a striking nppearimce. The surface was studded nll over with rounded nodules of Tlie abdomen was much distended. Heart.-Tho myocardium was in it condition of brown atrophy. The aortic niitl mitre1 cusps showed fibroid thickening. Lzcn(ls..--These were empliyscinatous, with a few patches of collapse. Tlicre was no growth in the rectum. Received Febrnaiy 2, 1912.
doi:10.1002/path.1700170105 fatcat:7gxjcbzwnvflzn5wsnwuiearqe