Brain MR imaging in systemic lupus erythematous

Hyun Ae Park, Kee Hyun Chang, Moon Hee Han, Kyung Hwon Lee, Sang Hoon Cha, Sung Kwon Kim, Jung Sang Lee
1992 Journal of the Korean Radiological Society  
To present MR imaging findings of intracranial lesions in systemic lupus erythem atosus (SLE) , a retrospective study was performed o n MR images of 33 SLE pa tients with neurologic symptoms and signs. MR imaging was performed on either a 0.5T (21 patient s) or 2.0T unit ( 12 patients) , u sin g T1-weighted , proton-density-weighted, and T2-weighted spin echo sequences in all patients . 1n seven patients, post-contrast T 1-weighted images were also obtained after administration of gadopentetate
more » ... dimeglumine. T he main MR findings consisted of fo cal. lesion s suggesting ischemia/infarct (15 patients) , diffu se brain atrophy (8) , and findings associated with infection (4). The MR findin gs were norm al in 11 patien ts (33 % ). The focal lesion s suggesting ischemialinfarcts presumably secondary to vasculiti s were distributed in the cortex or subcortical white matter (7 patients) , d eep periventrκul a r white matter (3) , or in both areas (5). Most ofthe fo callesions were multiple and small in size. The findings associated with infection were variable and included communicating hydrocephalus , m eningeal enhancem ent , granuloma , etc. MR findings of SLE were non-specific and therefore clinical correlation is needed when evalating SLE in MR . Index Words: Brain , M agnetic R eson ance lnm agin g 10. 1214 Brain , Lupus Erythematous 10. 6 1 Brain , vasculitis 10 .62 Brain , infarction 10.78 서 론 전신성 홍반성 낭창 ( syste mi c lupus erythematosus: SLE) 은 자가변역 질환 ( autoimmune di sease) 으로서 드 * 충북대학교 의과대학 방사선과학교실 물지 않게 혈관염 . 2차적 감염등에 의해 뇌병변이 발생한 다. 임상적으로 경련, 편두통, 시력장애, 국소신경증상, 정신이상 등의 임상 증세를 나타내 는데 감별진단으로는 약물유도현상 ( drug -induced phenomenon, 특히 스테로
doi:10.3348/jkrs.1992.28.5.658 fatcat:wqtrv6fejrbrvpwweqqy6agslm