Antipsychotic treatment was associated with higher risk of hospitalization for hyperglycemia (OR, 1.50; 95% CI 1.29-1.74, P<0.001), particularly for those who had just started treatment, in a case control study of patients aged 66 years or older. (Arch Intern Med [July 27, 2009] 169(14):1282) In an analysis of long term type 1 diabetes complications after 30 years of disease in the DCCT cohort, cumulative incidences of proliferative retinopathy, nephropathy, and cardiovascular disease were 21%,

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... 9%, and 9% compared with 50%, 25%, and 14%, respectively, after conventional therapy in the Pittsburgh Epidemiology of Diabetes Complications study. (Arch Intern Med [July 27, 2009] 169(14):1307) Continuous intraperitoneal insulin infusion with subcutaneous insulin in patients with type 1 diabetes results in a lower mean HbA1c (-0.76% [95% CI ؊1.41 to ؊0.11], P ‫؍‬ 0.03) compared with subcutaneous treatment; there was no difference in the rates of severe hypoglycemia in this 16-month randomized crossover study in 24 patients. (Diabetes Care [August 2009] 32(8):1372)