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Current Drug Targets
C u r r e n t D r u g T a r g e t s Abstract: Long known for its anti-nociceptive effects, the opioid -endorphin is also reported to have rewarding and reinforcing properties and to be involved in stress response. In this manuscript we summarize the present neurobiological and behavioral evidence regarding the role of -endorphin in stress-related psychiatric disorders, depression and PTSD. There is existing data that support the importance of -endorphin neurotransmission in mediatingdoi:10.2174/138945009789735147 pmid:19702553 fatcat:o7ylziqoznda7egrtaw2ybpyyy