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Using linkage maps to correct and scaffold de novo genome assemblies: methods, challenges, and computational tools
2015
Frontiers in Genetics
Frontiers website link: www.frontiersin.org Citation: Fierst JL(2015) Using linkage maps to correct and scaffold de novo genome assemblies: Methods, challenges and computational tools. ABSTRACT 2 Modern high-throughput DNA sequencing has made it possible to inexpensively produce 3 genome sequences, but in practice many of these draft genomes are fragmented and 4 incomplete. Genetic linkage maps based on recombination rates between physical markers 5 have been used in biology for over 100 years
doi:10.3389/fgene.2015.00220
pmid:26150829
pmcid:PMC4473057
fatcat:f5kf2ht4mjdsfg6rcltdvqfhti