Colorectal carcinoma in children and adolescents
Carcinoma colorrectal en niños y adolescentes

2021 Archivos Argentinos de Pediatria  
Although colorectal carcinoma (CRC) is the third most common type of cancer in adults, only 1-4 % of cases are reported in individuals younger than 25-30 years. Its presentation is usually confused with other diseases, leading to significant delays in diagnosis. Given its low incidence, few pediatricians will see a case throughout their practice. However, multiple hereditary syndromes during childhood predispose to CRC. The objective of this review is to provide an update on syndromes
more » ... ng to CRC. Screening indications will be reviewed because an early diagnosis during localized stages is the main prognostic factor. In addition, patient and family genetic counseling tools will be enhanced. In turn, the clinical and histological manifestations and prognostic factors typical of CRC in the pediatric population will be discussed. Although treatment guidelines are extrapolated from the adult experience, therapy guidelines will be summarized here.
doi:10.5546/aap.2021.eng.e487 pmid:34569749 fatcat:72qlhukhc5emrangz2fllicdem