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Ketamine in the treatment of cocaine use disorders

Ronaldo Cascelli Schelb Scalla Pereira, Emanuelle Emília Ferreira Parreiras, Davi Cascelli Schelb Scalla Pereira, João Eduardo Schelb Scalla Pere Cascelli, Thaila Vidal de Oliveira, Leonardo De Paula Junqueira, Valdinei Godinho Pereira, Marcelo Barcellos da Rosa, Tiago Ricardo Moreira, Marilane De Oliveira Fani Amaro, Bruno David Henriques, Camilo Amaro de Carvalho
2021 Ciência e Natura  

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ketamine is a dissociative anesthetic and, recently, its antidepressant properties has been described. Besides, its safety has been proven in the treatment of Stimulant Use Disorders. Objective: to evaluate the use of ketamine in the treatment of Stimulant Use Disorders (specially cocaine and its byproducts). Methods: patient's motivation for change was measured by URICA scale and psychiatric symptoms by EAS-40 score, both before and after the intervention. Results: it was verified, after the
more » ... mparison between the Readiness Score means, an increase in the motivation for change after ketamine's single administration, when compared to the moments before and after the intervention. Analyzing the Global Severity Index before and after ketamine administration, by EAS-40 score, we noticed a slight reduction of the psychiatric symptoms before and after the intervention. Conclusion: it was proven that ketamine's single administration led to a quick and lasting improvement on the user's motivation without worsening the mental health status.
doi:10.5902/2179460x44077 fatcat:j3zdppq5rzefndjuwmo4uv3vcq
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Ronaldo Cascelli Schelb Scalla Pereira, Emanuelle Emília Ferreira Parreiras, Davi Cascelli Schelb Scalla Pereira, João Eduardo Schelb Scalla Pere Cascelli, Thaila Vidal de Oliveira, Leonardo De Paula Junqueira, Valdinei Godinho Pereira, Marcelo Barcellos da Rosa, Tiago Ricardo Moreira, Marilane De Oliveira Fani Amaro, Bruno David Henriques, Camilo Amaro de Carvalho. "Ketamine in the treatment of cocaine use disorders." Ciência e Natura (2021) e22-44077