Hospital of New York, Coleman and DuBois2 have found that in typhoid fever the liberal diets proposed by Coleman and his collaborators3 occasion only a slight, if not negligible increase in heat production. It was quite unexpected to find that the large amount of food administered exhibits little or no specific dynamic action. In explanation of this result it is suggested that the stimulation of metabolism by the toxic agent is so intense that further stimulation by food is insignificant. The

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... ief theoretic objection to the use of the liberal diet in typhoid fever is thus set aside.