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SLE clusters had similar levels of nucleic acid-specific AAbs and Ro52 AAbs, but were distinguished by significant differences in histone 2A (H2A) AAb levels. Renal manifestations were significantly enriched in the NA Ro52 cluster and the AA nucleolin/histone cluster compared to other SLE patient clusters of the same ethnicity. Abstract THU0263 - Figure 1 Conclusion: Expanded AAb profiles can be used to identify SLE subsets that are more likely to have renal manifestations of disease.doi:10.1136/annrheumdis-2019-eular.5714 fatcat:qjwfxfkjs5cwrh6kdnemzrbsn4