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The Approach to Diarrhea
[chapter]
2007
Canine Internal Medicine Secrets
Metoclopramide is a commonly used antiemetic drug. It can be given by intermittent subcutaneous injection (0.2-0.4 mg/kg every 6 hours, subcutaneously [SQ] or intramuscularly [IM]) or as a constant intravenous infusion (1-2 mg/kg/day). The latter mode of administration appears to be more efficacious. This medication predominantly affects the D 2 dopaminergic receptors in the CRTZ and gut. It also affects the 5-HT 3 serotonergic receptors in the CRTZ. Phenothiazine drugs such as chlorpromazine
doi:10.1016/b978-1-56053-629-1.50038-8
fatcat:gf64fmml6rav5la7q36y26ernm