Clinical application of the sentinel lymph node technique in early ovarian cancer: a pilot study

V Lago, P Bello, B Montero, L Matute, P Padilla-Iserte, S Lopez, M Agudelo, S Domingo
2018 International Journal of Gynecological Cancer  
IntroductionThere is limited evidence favoring the use of the sentinel lymph node technique in ovarian cancer, and no standardized approach has been studied. The objective of the present pilot study is to determine the feasibility of the sentinel lymph node technique by applying a clinical algorithm.MethodsPatients with confirmed ovarian cancer were included. 99mTc and indocyanine green were injected into the ovarian and infundubulo-pelvic ligament stump. A gamma probe and near-infrared
more » ... ar-infrared fluorescence imaging were used for sentinel lymph node detection.ResultsThe sentinel lymph node technique was performed in nine patients with a detection rate in the pelvic and/or para-aortic region of 100%. The tracer distribution rates of sentinel lymph nodes in the pelvic and para-aortic regions were 87.5% and 70%, respectively.ConclusionThe detection of sentinel lymph nodes in early-stage ovarian cancer appears to be achievable. Based on these results, a clinical trial entitled SENTOV (SENtinel lymph node Technique in OVarian cancer) will be performed.
doi:10.1136/ijgc-2018-000049 pmid:30718316 fatcat:2xc67hejaffmzixhmbfu4mw7x4