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Quantitative estimation of AgNORs in normal, dysplastic and malignant oral mucosa
2014
Biomedical Papers of the Faculty of Medicine of Palacky University
Aims. Silver stainable nucleolar organizer regions (AgNORs) have received a great deal of attention recently as their frequency within the nuclei is significantly higher in malignant cells than in normal, reactive or benign neoplastic cells. The objective of this study was to carry out a quantitative assessment of large and small AgNORs in oral normal mucosa, precancerous lesions and infiltrating squamous cell carcinomas. Methods. The study comprised 110 formalin-fixed, paraffin-embedded oral
doi:10.5507/bp.2013.002
pmid:23446205
fatcat:uiw25v47zbhhbf64h7wuae5uuq