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3P056 Development of the line confocal system for the single molecule tracking of fast folding dynamics of proteins(01C. Protein: Property,Poster,The 52nd Annual Meeting of the Biophysical Society of Japan(BSJ2014))
3P056 タンパク質の高速折り畳みダイナミクスの一分子追跡を目指したライン共焦点顕微鏡の開発(01C. 蛋白質:物性,ポスター,第52回日本生物物理学会年会(2014年度))
2014
Seibutsu Butsuri
3P056 タンパク質の高速折り畳みダイナミクスの一分子追跡を目指したライン共焦点顕微鏡の開発(01C. 蛋白質:物性,ポスター,第52回日本生物物理学会年会(2014年度))
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Metadynamics (MTD) is an enhanced sampling algorithm applicable for the computational studies of biosystems with high energy barriers and slow modes of motion. It based on a history-dependent bias potential in a collective variable (CV) space. In particular, we are focused on multireplica approaches such as the bias-exchange MTD (BE-MTD), where the CV space is divided into lower dimensionality subspaces for efficiency and scalability. We demonstrate that BE-MTD can be improved (shorter
doi:10.2142/biophys.54.s258_2
fatcat:cddutxr245da3nuubfz3hfrtie