SYNTHESIS, CHARACTERIZATION AND ANTIBACTERIAL STUDIES OF AMINOBENZOTHIAZOLE DERIVATIVE AND ITS COPPER(II) COMPLEX

S. B. Rahardjo, M. K. Widowati, Y. A. Rasyda, S.D. Marliyana
2021 RASAYAN Journal of Chemistry  
This research aimed to synthesize and characterize Schiff base ligand (SB) derived from 2-aminobenzothiazole with o-anisaldehyde and its Cu(II) complex and investigate their antibacterial activities. The complex (Cu(II)-SB) was synthesized in a mole ratio of 1:2 of metal to the ligand. The complex's physical measurements included UV-Vis, Atomic Absorption Spectrophotometer (AAS), Thermogravimetric Analysis/Differential Thermal Analysis (TG/DTA), FTIR, electrical conductivity, and magnetic
more » ... tibility. The formation of the complex was indicated by a shift in the maximum wavelength of UV-Vis spectra toward smaller, from 823 nm for Cu(II) to 731 nm in the complex. The proposed complex formula was [Cu(SB)2]SO4·H2O. The IR spectral data on the Cu(II)-SB showed that SB was coordinated through the C=Nazomethine and C=Nthiazole functional groups. The magnetic moment result µeff of 2.07 B.M, indicated that the complex was paramagnetic and was expected to have square planar geometry. [Cu(SB)2]SO4·H2O exhibited the highest antibacterial activity than the ligands and metals.
doi:10.31788/rjc.2021.1436378 fatcat:4coijkiuqbf7xe57vwori4kbmu