Nasal septal tumors (benign or malignant) are rare diseases. The incidence of malignant nasal septal tumors is 2.7-8.4% of nasal and paranasal malignancies. [1] [2] [3] [4] [5] The symptoms of nasal septal tumors are usually nonspecific, such as nasal ob-struction or nasal bleeding. 1-3,5) The differential diagnosis of nasal septal tumors depends on various pathologies, ranging from benign tumors to malignant tumors. 1-6) Because of their rarity, discrepancies among clinical and histologic

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... ts of nasal septal tumors have occurred. 2,3) In addition, the precise treatment for nasal septal tumor remains unlcear. 5) Therefore, the objective of this study was to review the clinical characteristics and treatment outcomes of nasal septal tumors based on our 12-year experience. Background and Objectives The purpose of this study was to review the clinical characteristics and treatment outcomes of benign and malignant nasal septal tumors. Subjects and Methods A total of 34 patients who underwent the treatment for nasal septal tumor between 2004 and 2015 were included in this study. Demographic characteristics, sinonasal chief complaints, size and localization of nasal septal tumor, imaging findings, surgical method, histopathologic results, treatment outcomes, and postoperative complications were reviewed. Results Of the 34 patients with nasal septal tumor used in this study, 22 (64.7%) had benign tumors and 12 (35.3%) had malignant tumors. The most common sinonasal complaint of both benign and malignant nasal septal tumors was nasal obstruction. The most common benign tumor was inverted papilloma (n=7), whereas the most common malignant tumors were malignant melanoma (n=2), plasmacytoma (n=2), and metastatic carcinoma (n=2). All patients except two cases underwent endoscopic tumor removal. There were 4 recurrences in malignant nasal septal tumors. There was no recurrence in benign tumors. No major complications resulting from surgical intervention were found. Conclusion Endoscopic surgery with complete excision is a safe and effective procedure for benign nasal septal tumors. Recurrence is more common in malignant nasal septal tumor. Therefore, long term follow-ups with regular radiologic and endoscopic examinations are necessary for patients with malignant nasal septal tumor. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.