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Enhanced apoptosis by inhibition of cisplatin-induced autophagy in human bladder cancer cells
2016
Urological Science
Conclusion: High HK2 expression in bladder cancers induced oversecretion of lactate, which was associated with metastatic behaviors through the cancer stem cell formation, EMT promotion and nuclear translocation of phosphorylated NF-kB and Twist1. HK2 may be a novel oncoprotein and play as target for bladder cancer therapy.
doi:10.1016/j.urols.2016.05.063
fatcat:re75vyjarzdknjf4m2qhwo5ezm