The prevalence of Helicobacter pylori and its effect on prognosis of patients with COVID-19

Ahmed Bilal Genc, Selcuk Yaylaci, Hamad Dheir, Didar Senocak, Elif Ozozen, Kubilay Issever, Deniz Cekic, Havva Kocayigit, Cengiz Karacaer, Elif Kose, Ahmet Nalbant, Ali Tamer (+2 others)
2021 Medical Science and Discovery  
Objective: SARS-CoV-2 RNA positivity in stool in COVID-19 infection has been reported at rates varying between 6-83%. The purpose of this study was to determine the prevalence of H.pylori and investigate whether it determines the disease prognosis in COVID-19 patients. Methods: This study was conducted on 117 confirmed COVID-19 patients who were hospitalized due to symptomatic pneumonia and tested for stool H.pylori antigen. Stool H. pylori test outcomes, demographic parameters, laboratory
more » ... ngs, and prognostic predictors of disease were recorded. The effect of the presence of H.pylori in patients with COVID-19 was analyzed. Results: The mean age of 117 included patients was 49.68 ± 14.62 years, 78 (66.7%) had COVID PCR positivity and 32 (27.35%) had H.pylori positivity. There was no statistical difference in demographic data, prognosis, and laboratory parameters between those with and without H.pylori. Conclusion: H.pylori positivity was detected as 27.35% in patients with COVID-19 infection. However, we could not find the positive or negative effect of H.pylori on the prognosis of COVID-19 disease. In conclusion, according to the results of this study, H. pylori positivity or negativity neither determined the severity of the COVID-19 disease nor the poor prognostic indicators of the disease.
doi:10.36472/msd.v8i4.509 fatcat:l7qln5dcvvghzdaax2rjj4kv3q