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In much of the developed world, the HIV epidemic has largely been controlled by anti-retroviral treatment. Even so, there is growing concern that HIV-infected individuals may be at risk for accelerated brain aging, and a range of cognitive impairments. What promotes or resists these changes is largely unknown. There is also interest in discovering factors that promote resilience to HIV, and combat its adverse effects in children. Here we review recent developments in brain imaging that revealdoi:10.1007/s11904-015-0268-6 pmid:25902966 pmcid:PMC4433315 fatcat:f457wkwagzaxhev6tfq4yy4mni