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Modern electrophysiological recordings simultaneously capture single-unit spiking activities of hundreds of neurons spread across large cortical distances. Yet, this parallel activity is often confined to relatively low-dimensional manifolds. This implies strong coordination also among neurons that are most likely not even connected. Here, we combine in vivo recordings with network models and theory to characterize the nature of mesoscopic coordination patterns in macaque motor cortex and todoi:10.7554/elife.68422 pmid:35049496 pmcid:PMC8776256 fatcat:diwg6ofu5zfv3kuph2t3twm25e