Recovery of dialysis patients with COVID-19: Health outcomes 3 months after diagnosis in ERACODA

Marc H Hemmelder, Marlies Noordzij, Priya Vart, Luuk B Hilbrands, Kitty J Jager, Alferso C Abrahams, David Arroyo, Yuri Battaglia, Robert Ekart, Francesca Mallamaci, Sharon-Rose Malloney, Joao Oliveira (+223 others)
2022 Nephrology, Dialysis and Transplantation  
Background COVID-19-related short-term mortality is high in dialysis patients, but longer-term outcomes are largely unknown. We therefore assessed patient recovery in a large cohort of dialysis patients three months after their COVID-19 diagnosis. Methods We analyzed data on dialysis patients diagnosed with COVID-19 from February 1st, 2020-March 31st, 2021 from the European Renal Association COVID-19 Database (ERACODA). The outcomes studied were patient survival, residency, and functional- and
more » ... ental health status (estimated by their treating physician) three months after COVID-19 diagnosis. Complete follow-up data was available for 854 surviving patients. Patient characteristics associated with recovery were analyzed using logistic regression. Results In 2449 hemodialysis patients (mean ± SD age: 67.5 ± 14.4 years, 62% male) survival probabilities at three months after COVID-19 diagnosis were 90% for non-hospitalized patients (N = 1087), 73% for patients admitted to the hospital but not to an ICU (N = 1165) and 40% for those admitted to an ICU (N = 197). Patient survival hardly decreased between 28 days and three months after COVID-19 diagnosis. At three months, 87% functioned at their pre-existent functional and 94% at their pre-existent mental level. Only few of the surviving patients were still admitted to the hospital (between 0.8 and 6.3%) or a nursing home (approximately 5%). Higher age and frailty score at presentation and ICU admission were associated with worse functional outcome. Conclusions Mortality between 28 days and 3 months after COVID-19 diagnosis was low, and the majority of patients who survived COVID-19 recovered to their pre-existent functional and mental health level at three months after diagnosis.
doi:10.1093/ndt/gfac008 pmid:35030246 pmcid:PMC8807277 fatcat:eqej3fufeja3li7px3iiskq2lu