Update on Canine Idiopathic Pulmonary Fibrosis in West Highland White Terriers

Henna P. Laurila, Minna M. Rajamäki
2019 The Veterinary clinics of North America. Small animal practice  
Canine idiopathic pulmonary fibrosis (CIPF) is a chronic, progressive, interstitial lung disease (ILD) affecting older West Highland white terriers (WHWTs). According to one classification, CIPF is a familial fibrotic ILD in the group of idiopathic interstitial pneumonias. Etiology is unknown but likely arises from interplay between genetic and environmental factors. CIPF shares features with human idiopathic pulmonary fibrosis and human nonspecific interstitial pneumonia. This article
more » ... clinical signs, findings in physical examination, arterial oxygenation, diagnostic imaging, bronchoscopy, bronchoalveolar lavage, histopathology, disease course, and outcome of WHWTs with CIPF; compares canine and human diseases; summarizes biomarker research; and gives an overview of potential treatment.
doi:10.1016/j.cvsm.2019.11.004 pmid:31866093 fatcat:ibotxur6avhyfldhwousnaypx4