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Controlled release of dry reagents in porous media for tunable temporal and spatial distribution upon rehydration
2012
Lab on a Chip
Novel methods are demonstrated that enable controlled spatial and temporal rehydration of dried reagents in a porous matrix. These methods can be used in paper-based microfluidic assays to define reagent concentrations over time at zones downstream for improved performance, and can reduce costs by simplifying the manufacturing process with the use of a single porous substrate. First, the creation of uniform reagent pulses from patterned arrays of dried reagent is demonstrated. Second, reagents
doi:10.1039/c2lc40785j
pmid:22960691
pmcid:PMC3489279
fatcat:d3gb22souvgpjbgtgy5yrqnk7a