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Deoxyribonucleic acid (DNA) cryptography is becoming an emerging area in hiding messages, where DNA bases are used to encode binary data to enhance the randomness of the ciphertext. However, an extensive study on existing algorithms indicates that the encoded ciphertext has a low avalanche effect of providing a desirable confusion property of an encryption algorithm. This property is crucial to randomize the relationship between the plaintext and the ciphertext. Therefore, this research aims todoi:10.14569/ijacsa.2021.0121047 fatcat:tspsxlyhmbhr7ajfkzx3iqzgri