Internet of everything (IoE)-based smart services are expected to gain immense popularity in the future, which raises the need for next-generation wireless networks. Although fifth-generation (5G) networks can support various IoE services, they might not be able to completely fulfill the requirements of novel applications. Sixth-generation (6G) wireless systems are envisioned to overcome 5G network limitations. In this article, we explore recent advances made toward enabling 6G systems. We

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... e a taxonomy based on key enabling technologies, use cases, emerging machine learning schemes, communication technologies, networking technologies, and computing technologies. Furthermore, we identify and discuss open research challenges, such as artificial-intelligence-based adaptive transceivers, intelligent wireless energy harvesting, decentralized and secure business models, intelligent cell-less architecture, and distributed security models. We propose practical guidelines including deep Q-learning and federated learning-based transceivers, blockchain-based secure business models, homomorphic encryption, and distributed-ledgerbased authentication schemes to cope with these challenges. Finally, we outline and recommend several future directions. INDEX TERMS 6G, 5G, Internet of Things, Internet of Everything, federated learning, meta learning, blockchain.