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Comparison between PUN and Tofts models in the quantification of dynamic contrast-enhanced MR imaging
2012
Physics in Medicine and Biology
Dynamic contrast-enhanced study in magnetic resonance imaging (DCE-MRI) is an important tool in oncology to visualize tissues vascularization and to define tumour aggressiveness on the basis of an altered perfusion and permeability. Pharmacokinetic models are generally used to extract hemodynamic parameters, providing a quantitative description of the contrast uptake and wash-out. Empirical functions can also be used to fit experimental data without the need of any assumption about tumour
doi:10.1088/0031-9155/57/24/8443
pmid:23202297
fatcat:5lrfth4t6vh53knnjxe4t5urom