Aim: DIPSI (Diabetes in Pregnancy Study Group India ) guidelines recommends the non-fasting 75gms glucose tolerance test as a single step screening and diagnostic test for GDM. International Association of Diabetes and Pregnancy Study Group (IADPSG) guidelines states that when a pregnant women walks into the antenatal clinic in fasting state, fasting blood sugar has to be taken. Then 75gms oral glucose to be given and 1hr &2hr venous plasma glucose has to be taken. Fasting plasma glucose >

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... /dl, 1hr plasma glucose > 180mgs/dl or 2hr plasma glucose > 153mgs/dl diagnoses GDM. Our objective was to study the implications of implementing the IADPSG guidelines and DIPSI guidelines for screening and diagnosis of GDM in Indian population. Method: Prospective study of a total of 100 pregnant women attending AN clinic at GMKMCH, Salem from February 2016 to august 2016 underwent a 75gms OGTT in non-fasting state. Then after 2-3 days apart fasting, after 75gms glucose load 1hr & 2hr plasma glucose was taken. Venous plasma glucose was measured using an auto analyser and GDM was diagnosed by DIPSI and IADPSG criteria. Results: Among them 14% were diagnosed by DIPSI criteria. 9% were diagnosed by IADPSG criteria.4% were diagnosed by both. Diagnosis of GDM by IADPSG criteria leaves 5% undiagnosed which may be easily detected through DIPSI. Eventhough the DIPSI criteria detects more number of cases than IADPSG criteria, it is not statically significant. Because DIPSI method is practically easier to do which also detects more number of cases ,it is better than IADPSG method.