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The Preparation of Fluorescence-Quenched Probes for Use in the Characterization of Human Factor Xa Substrate Binding Domains
2004
Molecules
Preserved Fulltext
The preparation and characterization by LCMS of a library of 55 fluorescencequenched peptides is described. The peptides bear a terminal anthranilamide fluorophore and a penultimate 2,4-dinitrophenyl-L-lysine quencher, and will be used to probe the substrate binding domain of the human blood coagulation enzyme, factor Xa.
doi:10.3390/90600427
pmid:18007442
fatcat:xx5ktckccbff5mcfhm35nxrqsu