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Brainstem regulation of slow-wave-sleep
2017
Current Opinion in Neurobiology
Recent work has helped reconcile puzzling results from brainstem transection studies first performed over 60 years ago, which suggested the existence of a sleep-promoting system in the medullary brainstem. It was specifically shown that GABAergic neurons located in the medullary brainstem parafacial zone (PZ GABA ) are not only necessary for normal slow-wave-sleep (SWS) but that their selective activation is sufficient to induce SWS in behaving animals. In this review we discuss early
doi:10.1016/j.conb.2017.04.004
pmid:28500870
pmcid:PMC5607774
fatcat:3fqfg3k6aveyhi76xryg3htpfy