A Quantitative Metabolic Defect in Lipid Metabolism Associated with Abnormal Serum Lipoproteins in Man

MAX W. BIGGS, DAVID COLMAN
1953 Circulation  
Tritium-labeled cholesterol has been fed to a selected series of patients to demonstrate a quantitative metabolic defect in lipid metabolism in the presence of abnormal serum lipoprotein spectra. Patients with abnormal serum lipoprotein spectra carry a greater fraction of their newly absorbed cholesterol in the esterified form than do normals.
doi:10.1161/01.cir.7.3.393 pmid:13033068 fatcat:vk76ywgrqje2dpj6zbglyblmre