Chemical constituents of Lecythis pisonis and cytotoxic activity

Jocélia P. C. Oliveira, Éverton L. F. Ferreira, Mariana H. Chaves, Gardenia C. G. Militão, Gerardo M. V. Júnior, Arenice de M. Costa, Cláudia do Ó Pessoa, Manoel O. de Moraes, Letícia V. Costa-Lotufo
2012 Revista Brasileira de Farmacognosia  
The phytochemical investigation of the ethanol extract from leaves of Lecythis pisonis Cambess., Lecythidaceae, resulted in the isolation of seven triterpenes: α-and β-amyrin, uvaol and erythrodiol, ursolic and oleanolic acids and 3β-friedelinol (friedelan-3β-ol), as well as a mixture of sitosterol and stigmasterol steroids and a diterpene (E)-phytol. The structures of these compounds were identified by 1 H and 13 C NMR spectral analysis and compared with literature data. The mixture of
more » ... nes ursolic and oleanolic acids isolated from the active ethereal fraction showed moderate cytotoxic activity. This paper describes for the first time the phytochemical and cytotoxic study of Lecythis pisonis' leaves.
doi:10.1590/s0102-695x2012005000053 fatcat:4bc3qnmnnrca7neokxbbwntoeu