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Different Suppressive Effects of Fucoidan and Lentinan on IL-8 mRNA Expression inin VitroGut Inflammation
2009
Bioscience, biotechnology and biochemistry
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A system for assessing the anti-inflammatory effects of food factors was developed by establishing a coculture system with intestinal epithelial Caco-2 cells and macrophage RAW264.7 cells. The results indicate that fucoidan and lentinan exhibited different suppressive effects on interleukin-8 (IL-8) mRNA expression in Caco-2 through tumor necrosis factor-(TNF-) production from RAW264.7 stimulated with lipopolysaccharide (LPS).
doi:10.1271/bbb.90326
pmid:19809164
fatcat:7itwgrazpraodisxmpsxjq5k5q