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Susceptibility of radiation chimeras to Trypanosoma cruzi
1982
Infection and Immunity
Preserved Fulltext
Reciprocal bone marrow transfers were performed with C3H/HeJ mice, which are susceptible to infection with the Brazil strain of Trypanosoma cruzi, and resistant Ft (C3H/HeJ x C57BL/6J) mice. Mice reconstituted after lethal irradiation with syngeneic bone marrow displayed the resistance phenotype of the strain used, but neither C3H mice reconstituted with Ft bone marrow cells nor Fl mice reconstituted with C3H bone marrow cells survived challenge. Resistance to T. cruzi appears to be dependent
doi:10.1128/iai.36.2.844-846.1982
fatcat:ylphabyvdvfv3bta2yllixbx5i