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and Purpose-The relationship between diabetic retinopathy and ischemic stroke is uncertain and examined in this study. Methods-A population-based, prospective cohort study of 1617 middle-aged persons with diabetes. Diabetic retinopathy signs were ascertained from retinal photographs, and incident ischemic stroke events were prospectively identified and validated. Results-Over an average follow-up of 7.8 years, there were 75 ischemic stroke events. After adjustment for age, gender, race, center,doi:10.1161/01.str.0000254547.91276.50 pmid:17194880 fatcat:6ycwj34vzfebvhee2vf5perp4a