Impact of vancomycin MIC creep on patients with methicillin-resistant Staphylococcus aureus bacteremia

Yen-Cheng Yeh, Kuo-Ming Yeh, Te-Yu Lin, Sheng-Kang Chiu, Ya-Sung Yang, Yung-Chih Wang, Jung-Chung Lin
2012 Journal of Microbiology, Immunology and Infection  
Journal of Microbiology, Immunology and Infection (2012) 45, 214e220 Conclusion: We identified a significant upward trend in the use of vancomycin and its MIC over the last decade. This study shows that patients infected with MRSA isolates with high MICs (!1.5 mg/mL) do not have a significantly higher mortality rate compared with isolates with low MICs (<1.5 mg/mL).
doi:10.1016/j.jmii.2011.11.006 pmid:22571999 fatcat:3nyt27yhu5csnpzatfkynq33d4