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Journal of Microbiology, Immunology and Infection (2012) 45, 214e220 Conclusion: We identified a significant upward trend in the use of vancomycin and its MIC over the last decade. This study shows that patients infected with MRSA isolates with high MICs (!1.5 mg/mL) do not have a significantly higher mortality rate compared with isolates with low MICs (<1.5 mg/mL).doi:10.1016/j.jmii.2011.11.006 pmid:22571999 fatcat:3nyt27yhu5csnpzatfkynq33d4